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Regenerative Facials: Exosomes, PRP and Salmon DNA

What if your next facial didn’t just hydrate or exfoliate—but actually helped your skin rebuild itself? That’s the promise of regenerative skin treatments, and with the rise of collagen induction treatments including exosome facials, PRP / PRFM therapy, and PDRN, skincare has officially entered its next era.These aren’t just trends—they’re grounded in biostimulatory science, designed to activate the skin’s natural repair process rather than just masking signs of aging. The result? Smoother texture, brighter tone, and better elasticity.

The Base: Collagen Induction Therapy

We start here. At the heart of any effective regenerative facial is collagen induction therapy—a technique that stimulates the skin’s natural ability to repair and renew itself. While the term can include treatments like laser resurfacing, radiofrequency, and ultrasound-based tightening (such as Ultherapy), it most often refers to microneedling.

Microneedling works by creating controlled micro-injuries in the skin, triggering a cascade of biological healing responses that lead to increased collagen and elastin production. When paired with radiofrequency energy, as in Sylfirm X or Morpheus 8, this process becomes even more powerful—offering both collagen remodeling and subtle skin tightening in a single treatment.

Laser treatments such as the Sciton NanoPeel are also an effective base for a regenerative facial.

But what makes collagen induction therapy essential to regenerative facials is its ability to create microchannels that dramatically improve the absorption and performance of active topicals—whether that’s PRP, PRFM, exosomes, PDGF+, or PDRN. These regenerative ingredients go deeper, work harder, and deliver more visible results when paired with a delivery method that primes the skin to receive them.

In short: collagen induction therapy doesn’t just enhance the effects of regenerative facials—it enables them.

Exosome Facials

One of the most sought-after regenerative treatments today, the exosome facial uses stem cell-derived messengers to stimulate the skin’s own renewal process. These nano-sized vesicles—called exosomes—enhance communication between skin cells, triggering increased collagen and elastin production, reduced inflammation, and improved tone and texture.

We pair exosomes with laser treatments or RF microneedling to enhance absorption and boost results. The skin becomes visibly more radiant, firm, and smooth—often with minimal downtime. It is important to note that exosomes cannot be legally injected in the United States. 

Exosome facials are especially beneficial for:

  • Dull or uneven tone
  • Fine lines and mild laxity
  • Post-inflammatory pigmentation
  • Skin recovering from peels, lasers, or microneedling
  • Prejuvenation—preserving collagen before it declines

PRP / PRFM: Vampire Facials

We offer both PRP (Platelet-Rich Plasma) and PRFM (Platelet-Rich Fibrin Matrix)—two treatments that use your body’s own platelets to stimulate healing and collagen production. They can be injected or applied topically.

  • PRP is ideal for quick skin revitalization and is often used during these facials, especially when paired with RF microneedling.
  • PRFM takes it a step further, using a fibrin scaffold to slowly release growth factors over time, giving longer-lasting regenerative benefits.

Both treatments are commonly used to:

  • Rejuvenate delicate under-eye skin
  • Improve skin texture and tone
  • Support collagen production naturally

PDGF+ (Platelet-Derived Growth Factor) Facial

PDGF+ is a lab-purified, pharmaceutical-grade growth factor that enhances skin rejuvenation at the cellular level. Known for its role in angiogenesis—the formation of new blood vessels—PDGF+ increases oxygen and nutrient delivery to the skin, accelerating repair and stimulating collagen production. This results in firmer, more resilient skin with improved texture and tone.

As part of a regenerative facial, PDGF+ is typically delivered through microneedling or applied post-laser to maximize penetration and effectiveness. Its powerful regenerative properties make it especially effective for patients with fine lines, scarring, or post-procedure healing needs. By activating fibroblasts and supporting deep tissue repair, PDGF+ offers a targeted, evidence-based solution for smoother, stronger, and more youthful-looking skin.

Did you know? In the United States, it is only legal to inject PDGF+ and PRP / PRFM! Exosomes and PDRN are strictly for topical use. 

PDRN (Polydeoxyribonucleotide) Facial

Nicknamed the “salmon sperm facial” due to its origin from salmon DNA fragments, PDRN is a powerful bio-repair molecule that supports cell regeneration, hydration, and skin elasticity. It works by enhancing cellular turnover and stimulating the skin’s natural healing mechanisms, making it particularly effective for sensitive, aging, or damaged skin.

PDRN promotes tissue repair by binding to adenosine A2A receptors, which reduces inflammation and improves skin quality from within. The result is visibly plumper, healthier skin with enhanced moisture retention and improved resilience against environmental stressors.

Dr. Levine integrates PDRN into advanced facials to restore balance and vitality to compromised skin. With collagen induction treatments, PDRN therapy delivers long-term improvement in skin texture, tone, and elasticity—without downtime.

Who Benefits from Regenerative Facials?

The combination of collagen induction treatments with regenerative products – Regenerative Facials – are ideal for:

  • Improving results and reducing downtime after  energy-based treatments including laser peels
  • Patients looking to enhance skin quality
  • Patients looking to improve skin tone

All regenerative facials are tailored to your skin’s unique needs and sensitivities, and are safe for all skin tones.

Why Expertise Matters

As a double board-certified facial plastic surgeon and a recognized leader in regenerative aesthetics, Dr. Jennifer Levine brings a deep understanding of facial anatomy, harmony, and skin behavior to every treatment plan. Her innovation in the aesthetic use of exosomes earned her the prestigious RAES Award, and her protocols continue to reflect a commitment to science-backed, natural-looking results.

Schedule a Regenerative Facial

Layered on a collagen induction treatment, exosome facials, PRFM / PRP and PDRN skin boosters represent the new gold standard in skin pre- and rejuvenation. These treatments don’t just improve how your skin looks—they improve how it functions.

Whether you’re looking to boost your glow, restore firmness, or strengthen your skin’s long-term resilience, regenerative facials offer a smarter, more sustainable approach to skin health.

Curious which regenerative treatment is right for your skin? Schedule a consultation to explore what’s possible.