PDGF+

Conveniently located to serve the areas of New York, NY

Your skin is constantly renewing itself—but as we age, this process slows down, leading to fine lines, loss of elasticity, and slower healing after treatments or surgery. Ariessence Pure PDGF+ harnesses the power of Platelet-Derived Growth Factor (PDGF) to enhance cellular regeneration, boost collagen production, and accelerate healing.

This pharmaceutical-grade growth factor works synergistically with Hyaluronic Acid (HA) to deeply hydrate, firm, and rejuvenate the skin, making it an ideal post-procedure treatment following microneedling, laser resurfacing, and facelift surgery.

Jennifer Levine, MD offers Ariessence Pure PDGF+ as part of her customized approach to skin rejuvenation, helping patients achieve faster recovery and long-lasting skin renewal.

What Is Platelet-Derived Growth Factor (PDGF)?

PDGF growth factor is a naturally occurring protein essential for collagen production, wound healing and tissue regeneration. As one of the body’s most powerful regenerative compounds, PDGF stimulates fibroblast activity to strengthen and restore skin structure.

Ariessence Pure PDGF+ is a highly concentrated, pharmaceutical-grade formulation, ensuring maximum absorption and effectiveness. PDGF+ is designed to:

  • Trigger deep collagen renewal, strengthening skin structure.
  • Enhance microcirculation, bringing oxygen and nutrients to the skin.
  • Support faster cell turnover, leading to visibly smoother, younger-looking skin.

Benefits of PDGF

As a platelet growth factor, PDGF is a well-researched regenerative protein known for its ability to accelerate wound healing and stimulate collagen production. It plays a key role in tissue repair, making it an excellent choice for amplifying results of skin rejuvenation treatments and enhancing healing.

Key Benefits of PDGF+ Treatment

  • Enhanced Healing & Recovery – Reduces redness, swelling, and downtime after cosmetic procedures.
  • Collagen & Elastin Stimulation – Strengthens skin structure for improved firmness and elasticity.
  • Hair Restoration & Growth – Stimulates hair follicle activity, improves scalp circulation, and increases hair density. 
  • Improved Skin Texture & Tone – Smooths fine lines, acne scars, and uneven pigmentation.
  • Scar Minimization – Supports tissue repair, leading to cleaner, more refined healing after surgery.

Hyaluronic Acid Synergy: Hydration & Skin Barrier Protection

While PDGF alone offers powerful regenerative properties, Dr. Levine elects to use Ariessence Pure PDGF+ because it is formulated with Hyaluronic Acid (HA), a naturally occurring molecule known for its hydrating and plumping effects. This enhances results by:

  • Strengthening the skin barrier, reducing moisture loss.
  • Enhancing penetration of growth factors, maximizing their effects.
  • Promoting long-term skin hydration, leading to a supple, glowing complexion.

Together, PDGF+ and HA provide a multifaceted approach to skin repair and rejuvenation that improves both structure and hydration—making it a perfect complement to post-procedure recovery.

Who Is a Candidate for PDGF+?

This treatment is ideal for individuals who want to:

  • Improve skin texture, hydration, and elasticity.
  • Reduce fine lines, wrinkles, and signs of aging.
  • Minimize post-procedure inflammation and scarring, enhancing their results.

Because it is non-invasive and compatible with all skin types, PDGF+ can be customized to fit individual aesthetic goals.

Corresponding Treatments & Procedures

RF Microneedling with PDGF+

RF Microneedling takes traditional microneedling a step further by delivering radiofrequency energy into deeper skin layers, amplifying collagen remodeling and skin tightening. This process not only stimulates the skin’s natural healing response but also creates micro-channels that allow for deeper absorption of regenerative treatments like Ariessence Pure PDGF+.

Applying PDGF+ immediately after treatment enhances these effects by:

  • Accelerating skin renewal at a deeper level by delivering growth factors directly into micro-injuries.
  • Enhancing tissue repair, reducing redness and minimizing downtime.
  • Boosting skin firmness and elasticity, as RF energy contracts collagen fibers for a more lifted appearance.
  • Refining pores and improving overall texture, leading to more noticeable, long-lasting results.

By combining RF Microneedling with PDGF+, patients achieve smoother, firmer, and more youthful-looking skin with optimized post-procedure recovery.

Hair Restoration & Growth with PDGF+

PDGF+ is a powerful regenerative treatment for thinning hair, stimulating hair follicle activity, improving scalp circulation, and enhancing hair density. When applied using advanced medical techniques, PDGF+ supports stronger, healthier hair growth and helps reduce thinning over time.

Dr. Jennifer Levine integrates PDGF+ into hair restoration treatments through two proven methods:

  • Scalp Injections – Directly delivers PDGF+ into the scalp, activating dormant hair follicles, increasing blood supply, and strengthening existing hair.
  • Microneedling with PDGF+ – Creates micro-channels in the scalp, allowing for deeper penetration of PDGF+, enhancing its ability to stimulate follicle repair and boost hair regrowth.

These treatments are often combined with other hair restoration therapies, including hair supplements, creating a comprehensive approach to achieving fuller, thicker hair.

Laser Resurfacing with PDGF+

Laser resurfacing treatments like Sciton and Frax deliver controlled energy to the skin, stimulating collagen production, resurfacing older skin layers and improving tone and texture. These treatments target concerns like fine lines, sun damage, uneven pigmentation, and skin laxity by triggering the body’s natural healing response.

Incorporating PDGF+ immediately after laser treatments enhances these effects by:

  • Deepening collagen stimulation, amplifying the laser’s ability to firm and tighten the skin.
  • Accelerating cellular regeneration, optimizing skin renewal for a smoother, more even texture.
  • Hydrating and fortifying the skin barrier, reducing post-laser dryness and sensitivity.
  • Minimizing inflammation and redness, ensuring a more comfortable recovery while maintaining the integrity of results.

By pairing PDGF+ with ablative or non-ablative laser treatments, patients experience enhanced skin rejuvenation, improved long-term outcomes, and a visibly healthier complexion.

Enhancing Surgical Results with PDGF+

Dr. Levine integrates a proprietary PDGF+ technique during facelifts and surgical lifts, enhancing healing, collagen regeneration, and overall skin renewal for optimal post-surgical results.

Facial Rejuvenation with PDGF+

Dr. Levine strategically injects PDGF+ into the under-eye area and nasolabial folds to promote natural skin regeneration. This enhances skin quality, texture, and firmness over time, offering a subtle yet long-lasting rejuvenation.

Similar to PRP (Platelet-Rich Plasma) used in treatments like the Vampire Facial, PDGF+ stimulates collagen production, strengthens skin integrity, and smooths fine lines for a refreshed, youthful appearance. However, the key difference is that PRP is derived from the patient’s own blood, while PDGF+ is a highly purified, lab-derived growth factor. This allows PDGF+ to deliver a more consistent and potent concentration of growth factors compared to PRP, leading to enhanced collagen stimulation and more predictable results.

Did you know? The skin around the eyes is the thinnest on the body, making it more prone to fine lines, wrinkles, laxity, and pigmentation. By boosting collagen and supporting tissue regeneration, PDGF+ helps restore firmness and resilience to this delicate area.

FAQs

Is PDGF+ a filler?

​​No, PDGF+ is not a filler. While it is injected into the skin, PDGF+ (Platelet-Derived Growth Factor) works by stimulating your body’s natural collagen production rather than adding volume. This enhances skin quality, firmness, and elasticity over time, making it an ideal option for natural skin rejuvenation without the use of traditional fillers.

PDGF vs. PRP/PRFM: What is the difference?

Platelet-Rich Plasma (PRP) / Platelet-Rich Fiber Matrix (PRFM) is derived from a patient’s own blood and contains a mix of growth factors, cytokines, and bioactive proteins, including PDGF. The concentration of these growth factors can vary depending on individual health and platelet levels.

Ariessence Pure PDGF+ is a pharmaceutical-grade formulation that provides a consistent and highly concentrated dose of PDGF for predictable, targeted skin renewal. Unlike PRP / PRFM, PDGF+ does not require a blood draw, making the process simpler and more efficient for post-procedure recovery and skin rejuvenation.

Both PRP and PDGF+ stimulate collagen production and tissue repair, and Dr. Levine may recommend one or both treatments based on your aesthetic goals and treatment plan.

PDGF vs. Exosome Therapy: What is the difference?

Both PDGF and exosome therapy are used to stimulate skin regeneration, but they differ in mechanism and application.

PDGF+ (Platelet-Derived Growth Factor) stimulates collagen production and accelerates wound healing. It works by activating fibroblasts, the cells responsible for tissue repair and collagen remodeling. PDGF+ is particularly beneficial for post-procedure healing, scar minimization, and strengthening skin structure.
Exosome therapy enhances cell communication by delivering extracellular vesicles containing a complex mix of growth factors, peptides, and genetic signals. Exosomes promote skin rejuvenation at a broader level, influencing overall cellular function, hydration, and inflammation reduction.

Since PDGF+ focuses on targeted tissue repair and collagen synthesis, and exosomes support broader skin regeneration, Dr. Levine may integrate both therapies to enhance skin renewal, improve healing, and deliver long-term regenerative benefits.

Is PDGF+ safe?

Yes, PDGF is a naturally occurring growth factor that has been widely studied for its regenerative effects. Ariessence Pure PDGF+ is specially formulated for cosmetic use and is considered safe for all skin types.